Immunity and vaccines against sexually transmitted Chlamydia trachomatis infection

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Immunity and vaccines against sexually transmitted Chlamydia trachomatis infection.

PURPOSE OF REVIEW The aim is to review recent findings on immunity and vaccine development to Chlamydia trachomatis. RECENT FINDINGS There is increasing knowledge on the interactions between C. trachomatis and infected host cells. During genital infection the organism avoids generating protective immunity but immune responses to a number of chlamydial proteins have been associated with reprod...

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Immunity, immunopathology, and human vaccine development against sexually transmitted Chlamydia trachomatis

This review examines the immunity, immunopathology, and contemporary problems of vaccine development against sexually transmitted Chlamydia trachomatis. Despite improved surveillance and treatment initiatives, the incidence of C. trachomatis infection has increased dramatically over the past 30 years in both the developed and developing world. Studies in animal models have shown that protective...

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Vaccines against sexually transmitted diseases

Introduction Human sexually transmitted infections are prevalent throughout the world. Several have been associated with adverse pregnancy outcome and increased susceptibility to HIV infection, in addition to the discomfort of inflammation of the genital tract. Yet vaccines to protect against the infection at the genital mucosa are not available. Hepatitis B is an exception, but this virus beco...

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Chlamydia trachomatis Infection, Immunity, and Pregnancy Outcome

Chlamydia trachomatis can ascend from the cervix to the fallopian tubes and survive for long periods of time without causing symptoms. The immune response to infection clears the extracellular organisms but leads to development of a persistent intracellular infection. Repeated cycles of productive infection and persistence eventually induce tubal occlusion and infertility. Persistently infected...

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Detection of Chlamydia trachomatis infection in patients seen at a sexually transmitted infection clinic.

esthetic outcome, but would also prevent collapse with inspiration. This could be overcome by adding a free cartilage graft from the concha of auricle or a titanium mesh, although such procedures were considered unnecessary in this case given the age of the patient. Other reconstruction options requiring a single intervention are nasolabial transposition flap or subcutaneous turnover pedicle, b...

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ژورنال

عنوان ژورنال: Current Opinion in Infectious Diseases

سال: 2011

ISSN: 0951-7375

DOI: 10.1097/qco.0b013e3283421081